Physiologic constraints of using exosomes in vivo as systemic delivery vehicles
نویسندگان
چکیده
منابع مشابه
Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges
Exosomes are small intracellular membrane-based vesicles with different compositions that are involved in several biological and pathological processes. The exploitation of exosomes as drug delivery vehicles offers important advantages compared to other nanoparticulate drug delivery systems such as liposomes and polymeric nanoparticles; exosomes are non-immunogenic in nature due to similar comp...
متن کاملExosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA
CagA, encoded by cytotoxin-associated gene A (cagA), is a major virulence factor of Helicobacter pylori, a gastric pathogen involved in the development of upper gastrointestinal diseases. Infection with cagA-positive H. pylori may also be associated with diseases outside the stomach, although the mechanisms through which H. pylori infection promotes extragastric diseases remain unknown. Here, w...
متن کاملAn Update on in Vivo Imaging of Extracellular Vesicles as Drug Delivery Vehicles
Extracellular vesicles (EVs) are currently being considered as promising drug delivery vehicles. EVs are naturally occurring vesicles that exhibit many characteristics favorable to serve as drug delivery vehicles. In addition, EVs have inherent properties for treatment of cancers and other diseases. For research and clinical translation of use of EVs as drug delivery vehicles, in vivo tracking ...
متن کاملNerve guidance channels as drug delivery vehicles.
Nerve guidance channels (NGCs) have been shown to facilitate regeneration after transection injury to the peripheral nerve or spinal cord. Various therapeutic molecules, including neurotrophic factors, have improved regeneration and functional recovery after injury when combined with NGCs; however, their impact has not been maximized partly due to the lack of an appropriate drug delivery system...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Precision Nanomedicine
سال: 2019
ISSN: 2639-9431
DOI: 10.33218/prnano2(3)070819.1